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British Journal of Anaesthesia, 1978, Vol. 50, No. 9 931-935
© 1978 The Board of Management and Trustees of the British Journal of Anaesthesia

other

COMPARATIVE ASSESSMENT OF FENOPROFEN AND PARACETAMOL GIVEN IN COMBINATION FOR PAIN AFTER SURGERY

I. T. DAVIE, M.B., CH.B., F.F.A.R.C.S. and N.H. GORDON, M.B., CH.B., F.F.A.R.C.S.

Department of Anaesthesia, Western General Hospital Edinburgh

In a double-blind study of patients suffering from pain after surgery, fenoprofen 200 mg and paracetamol 500 mg was compared with each drug given separately and with a placebo. There was a significant difference between the combination and the placebo, whereas, separately, the drugs were only marginally better than the placebo in relieving pain. There was a significant linear trend indicating a better clinical result as the number of active components in the regimen was increased.


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