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British Journal of Anaesthesia, 1978, Vol. 50, No. 9 925-929
© 1978 The Board of Management and Trustees of the British Journal of Anaesthesia


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EVALUATION OF THREE PREPARATIONS OF ETOMIDATE

M. ZACHARIAS, M.B., B.S., M.S(ANAESTH.), F.F.A.R.C.S., R. S. J. CLARKE, M.D., PH.D., F.F.A.R.C.S., J. W. DUNDEE, M.D., PH.D., F.F.A.R.C.S., M.R.C.P. and S. B. JOHNSTON, B.SC, M.B., B.CH.

Department of Anaesthetics, The Queen's University of Belfast

Three formulations of etomidate were evaluated in unpremedicated patients undergoing minor gynaecological procedures. There was a high frequency of pain on injection (up to 50%)and excitatory phenomena (up to 95%) with all formulations. The frequency of excitatory phenomena was significantly greater than that after methohexitone. Recovery was rapid, but emetic sequelae were frequent and significantiy more marked than after methohexitone.


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