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British Journal of Anaesthesia, 1977, Vol. 49, No. 9 945-949
© 1977 The Board of Management and Trustees of the British Journal of Anaesthesia

other

PREOPERATIVE SERUM CHOLINESTERASE CONCENTRATION IN CHRONIC RENAL FAILURE

Clinical experience of suxamethonium in 81 patients undergoing renal transplant

D. W. RYAN, M.B., CH.B., F.F.A.R.C.S.

Department of Anaesthesia, Royal Victoria Infirmary Newcastle upon Tyne

Serum cholinesterase concentrations were measured in 181 patients in chronic renal failure. Significant differences in cholinesterase concentrations were not found in patients undergoing dialysis and changes appear to be independent of the method of treatment used. Clinical experience with suxamethonium to facilitate tracheal intubation was satisfactory in 80 patients undergoing renal transplant. Apnoea occurred in one patient who was found subsequently to have atypical cholinesterase inheritance.


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