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British Journal of Anaesthesia, 1977, Vol. 49, No. 9 907-912
© 1977 The Board of Management and Trustees of the British Journal of Anaesthesia

other

COMPARISON OF I.V. DIAZEPAM AND HYDROXYZINE AS SURGICAL PREMEDICANTS

R. H. WENDER, M.D., J. T. CONNER, M.D., J. W. BELLVILLE, M.D., D. SCHEHL, R.N., F. DOREY, PH.D. and R. L. KATZ, M.D.

University of California at Los Angeles Los Angeles, California 90024, U.S.A.

Diazepam and hydroxyzine as i.v. surgical premedicants were compared. A double-blind randomized sequence was used employing 7.5 and 15 mg of diazepam {nu}. 75 and 150 mg of hydroxyzine. Each group consisted of 35 patients. Anxiety relief, sedation, lack of recall and patient acceptance were the principal assessments. Diazepam was superior to hydroxyzine in all respects. No serious side-effects were noted with either drug.


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