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British Journal of Anaesthesia, 1977, Vol. 49, No. 12 1235-1238
© 1977 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

EFFECTS OF VARYING INSPIRATORY FLOW WAVEFORM AND TIME IN INTERMITTENT POSITIVE PRESSURE VENTILATION III: BLOCKADE OF THE AUTONOMIC NERVOUS SYSTEM

A. B. BAKER, F.F.A.R.A.C.S.*, R. W. COWIE, F.F.A.R.A.C.S.{dagger} and J. E. COLLISS, F.F.A.R.c.s.*

Nuffield Department of Anaesthetics, University of Oxford.

The autonomic nervous system was blocked in dogs which were exposed to independent alterations in inspiratory flow waveform and time whilst being ventilated artificially at a constant volume and frequency. There were statistically significant differences in cardiac ouptut between the control and blocked states, but these differences were not of marked physiological significance. Alteration in inspiratory waveform or time in the blocked animals did not alter cardiac output significantly.

*Present address:Department of Anaesthesia, University of Otago, New Zealand.

{dagger}Present address:St Vincent's Hospital, Melbourne, Australia.


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