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British Journal of Anaesthesia, 1973, Vol. 45, No. 4 369-375
© 1973 The Board of Management and Trustees of the British Journal of Anaesthesia

other

SUBANAESTHETIC DOSAGE OF PROPANIDID AS A SEDATIVE FOR DENTISTRY: A CONTROLLED CLINICAL TRIAL

P. S. COSSHAM, M.B.CH.B., F.F.A.R.C.S.* and R. A. DIXON, B.Sc., PH.D., F.S.S.

Department of Anaesthetics, Royal Infirmary Sheffield, S6 3DA
Department of Community Medicine, The University Sheffield. S10 2TN

*Present address: Groby Road Hospital, Leicester.

At over 60 sessions of outpatient dentistry at which a technique employing incremental subanaesthetic doses of propanidid was used, less amnesia but equivalent anxiolytic effect was apparent in comparison with a similar number of sessions before which a single dose of diazepam was given. Apart from some patient movement and shivering with propanidid, operating conditions were no worse. No problems were experienced in maintaining an efficient airway. Blood pressure falls were less common but tachycardia was more common with propanidid. Postoperative recovery was much more rapid, and after-effects, except for thrombophlebitis, were less common.


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