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British Journal of Anaesthesia, 1971, Vol. 43, No. 7 709-712
© 1971 The Board of Management and Trustees of the British Journal of Anaesthesia

case-report

ADRENALINE-INDUCED PULMONARY OEDEMA AND ITS TREATMENT

A Report of Two Cases

NAMK ERSOZ and S. C. FINESTONE

Department of Anesthesiology, Montefiore Hospital Pittsburgh, Pennsylvania, U.S.A

Pulmonary oedema developed suddenly in two healthy male patients undergoing elective surgery, following the inadvertent injection of large doses of adrenaline. Both patients showed an immediate and dramatic response to treatment with intravenous chlorproma-zine. The pathophysiology of pulmonary oedema, and the pharmacology of its production by adrenaline overdose, as well as the effects of both adrenaline and chlorpromazine on the pulmonary and systemic circulation will be discussed


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