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British Journal of Anaesthesia, 1971, Vol. 43, No. 12 1191-1194
© 1971 The Board of Management and Trustees of the British Journal of Anaesthesia

case-report

THIOPENTONE ANAPHYLAXIS

J. DAVIS, F.F.A.R.C.S.

Department of Anaesthetics, University of Birmingham Birmingham B15 2TH, England

A severe anaphylactic response occurred following intravenous injection of thiopentone in a patient who had been taking an oral barbiturate for a long time. The immediate management of the case included airway maintenance and oxygenation, restoration of fluid balance, together with administration of steroids and antihistamines. Postoperative mechanical ventilation of the lungs was continued for 4 hours until the signs of anaphy-laxis had subsided. Attention is drawn to some of the factors which may precipitate the reaction, and the evolution of modern views on the mechanisms of anaphiylaxis is given.


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Volume 100: Case reports: should they be confined to the dustbin?
Br. J. Anaesth., June 1, 2008; 100(6): 744 - 746.
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