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British Journal of Anaesthesia, 1971, Vol. 43, No. 12 1113-1120
© 1971 The Board of Management and Trustees of the British Journal of Anaesthesia

other

OXYGEN CONSUMPTION DURING CARDIOPULMONARY BYPASS WITH MODERATE HYPOTHERMIA IN MAN

E. A. HARRIS, M.D., PH.D., M.R.C.P., F.R.A.C.P., EVE R. SEELYE, B.A., M,.B., F.F.A.R.O.S. and A. W. SQUIRE, M.B., F.F.A.R.A.C.S.

Department of Clinical Physiology, Green Lane Hospital Auckland, 3, New Zealand

Oxygen consumption was measured during hypothermic total body perfusion in twenty-seven patients undergoing cardiac operations. In nine patients it was also measured immediately before induction of anaesthesia. Fourteen patients were kept at normal temperature for from 5 to 17 minutes after bypass began; the rest were cooled immediately to 30 °C. Oxygen consumption during bypass at normothermia, whether before or after cooling, was 84 per cent of the pre-anaesthesia value, due possibly to the effects of muscle relaxation. During hypothermia, patients who were cooled immediately had an oxygen consumption which was about 15 per cent lower than that found in the patients with delayed cooling. Even in the latter group, oxygen consumption during hypothermia probably did not quite meet requirements, since it was shown to be positively correlated with blood flow.


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