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British Journal of Anaesthesia, 1962, Vol. 34, No. 6 391-394
© 1962 The Board of Management and Trustees of the British Journal of Anaesthesia

other

CLINICAL STUDIES OF INDUCTION AGENTS

II: A COMPARISON OF THE INCIDENCE OF INDUCTION COMPLICATIONS WITH TWO METHYLATED OXYBARBITURATES, NARCONUMAL AND NARCODORM

DAVID W. BARRON

Department of Anaesthetics, The Queen's University of Belfast Northern Ireland

Narconumal and Narcodorm are methylated oxy-barbiturates which are closely related chemically. The induction characteristics of these compounds are compared with each other and with thiopen-tone as the standard drug. Both drugs behave in a similar manner to other methylated oxybar-biturates, e.g. hexobarbitone and methohexi-tone, in that they produce a fairly high incidence of excitatory phenomena. These are more marked with atropine as the sole premedicant than with opiate premedication. Hypotension is a common finding with both compounds. Narcodorm is slightly more potent than Narconumal because of the bromine atom in the former.


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