Skip Navigation


BJA Advance Access originally published online on September 28, 2009
British Journal of Anaesthesia 2009 103(5):750-754; doi:10.1093/bja/aep263
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
103/5/750    most recent
aep263v1
Right arrow E-Letters: Submit a response to the article
Right arrow E-letters: View responses
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Kim, S. Y.
Right arrow Articles by Kil, H. K.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kim, S. Y.
Right arrow Articles by Kil, H. K.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?


© The Author [2009]. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournal.org

Comparison of intrathecal fentanyl and sufentanil in low-dose dilute bupivacaine spinal anaesthesia for transurethral prostatectomy

S. Y. Kim1, J. E. Cho1, J. Y. Hong1,2, B. N. Koo1,2, J. M. Kim1 and H. K. Kil1,2,*

1 Department of Anaesthesiology and Pain Medicine and
2 Anaesthesia and Pain Research Institute, Yonsei University College of Medicine, 250 Seongsan-no, Seodaemun-gu, Seoul 120-752, Republic of Korea

* Corresponding author. E-mail: hkkil{at}yuhs.ac

Background: The administration of low-dose bupivacaine can limit the distribution of spinal block to reduce adverse haemodynamic effects. Intrathecal opioids can enhance analgesia in combination with subtherapeutic doses of local anaesthetics. We aimed at comparing the efficacy of intrathecal fentanyl and sufentanil with low-dose diluted bupivacaine for transurethral prostatectomy (TURP) in elderly patients.

Methods: Seventy patients undergoing TURP were randomly allocated into two groups. Group F (n=35) received fentanyl 25 µg+bupivacaine 0.5% (0.8 ml)+normal saline 0.3 ml and Group S (n=35) received sufentanil 5 µg+bupivacaine 0.5% (0.8 ml)+normal saline 0.7 ml—in total, bupivacaine 0.25% (1.6 ml) intrathecally. Onset and duration of the sensory block, the degree of the motor block, side-effects, and the perioperative analgesic requirements were assessed.

Results: The median peak level of the sensory block was significantly higher in Group S than in Group F (P=0.049). Group S required fewer perioperative analgesics than Group F (P=0.008). The time to the first analgesic request was longer in Group S (P=0.025). There were no differences between the groups for the onset and recovery time of the sensory block, degree of the motor block, quality of anaesthesia, or adverse effects.

Conclusions: Low-dose diluted bupivacaine with fentanyl 25 µg or sufentanil 5 µg can provide adequate anaesthesia without haemodynamic instability for TURP in elderly patients. However, sufentanil was superior to fentanyl in the quality of the spinal block produced.

Keywords: anaesthetic techniques, subarachnoid; anaesthetics local, bupivacaine; analgesics opioid, fentanyl; analgesics opioid, sufentanil; surgery, urological


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


E-letters:

Read all E-letters

Type of resectoscope in determining the necessary level of sensory block for TURP
Seza Apiliogullari, et al.
British Journal of Anaesthesia, 18 Nov 2009 [Full text]

Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.