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BJA Advance Access originally published online on June 25, 2009
British Journal of Anaesthesia 2009 103(3):369-370; doi:10.1093/bja/aep167
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© The Author [2009]. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournal.org

Meperidine-induced serotonin syndrome in a susceptible patient

S.-L. Guo1, T.-J. Wu1, C.-C. Liu2, C.-C. Ng2, C.-C. Chien2,3 and H.-L. Sun2,3,*

1 Department of Anesthesiology, Cathay General Hospital, 280 Renai Rd, Sec. 4, Taipei 10630, Taiwan, Republic of China
2 Department of Anesthesiology, Cathay General Hospital Sijhih, No. 2, Lane 59, Jiancheng Rd, Sijhih City, Taipei County 22174, Taiwan, Republic of China
3 School of Medicine, Fu-Jen Catholic University, 510 Chung Cheng Rd, Hsinchuang, Taipei County 24205, Taiwan, Republic of China

* Corresponding author. E-mail: hlsun{at}cgh.org.tw

We present a patient with a history of clomipramine-induced serotonin syndrome 5 yr prior who developed serotonin syndrome after a single dose of meperidine. This report heightens appreciation of population at risk and also recognition of potential toxicity in meperidine.

Keywords: analgesics opioid, meperidine; complications, serotonin syndrome


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Meperidine induced serotonin syndrome
David M Christmas, et al.
British Journal of Anaesthesia, 6 Nov 2009 [Full text]
Meperidine (pethidine) and toxicity
P Ken Gillman
British Journal of Anaesthesia, 4 Jan 2010 [Full text]

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