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BJA Advance Access originally published online on July 10, 2008
British Journal of Anaesthesia 2008 101(3):296-310; doi:10.1093/bja/aen203
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 BJA: September 2008
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© The Board of Management and Trustees of the British Journal of Anaesthesia 2008. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Recent developments in the perioperative management of adult patients with chronic kidney disease

R. G. Craig* and J. M. Hunter

Division of Clinical Science (Anaesthesia), University Clinical Department, University of Liverpool, The Duncan Building, Daulby Street, Liverpool L69 3GA, UK

* Corresponding author. E-mail: argcraig77{at}btinternet.com

The complications of chronic kidney disease (CKD) present the anaesthetist with a number of clinical challenges related in part to altered drug handling and to difficulties with vascular access and fluid balance. Safe anaesthetic management requires an understanding of CKD pathophysiology to prevent aggravation of pre-existing disease. This review will consider some recent changes in the management of adult patients with CKD as they affect the anaesthetist. It will consider medical problems associated with CKD together with new developments in perioperative management.

Keywords: anaesthesia, general; blood, coagulation; cardiovascular system, effects; kidney, failure


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