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British Journal of Anaesthesia 2008 100(1):17-22; doi:10.1093/bja/aem344
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Published by Oxford University Press 2008

Anaesthesia chapter from Saving Mothers' Lives; reviewing maternal deaths to make pregnancy safer

G. M. Cooper1,* and J. H. McClure2

1 University of Birmingham and Birmingham Women's Hospital, Birmingham, UK
2 Royal Infirmary of Edinburgh, Edinburgh, UK

* Corresponding author. E-mail: gcooper{at}rcanae.org.uk

This chapter concerning maternal mortality due to anaesthesia, reprinted with permission from Saving Mothers' Lives, is the 18th in a series of reports within the Confidential Enquiries into Maternal and Child Health (CEMACH) in the UK. In the years 2003–05 there were six women who died from problems directly related to anaesthesia, which is the same as the 2000–02 triennium. Obesity was a factor in four of these women who died. Two of these deaths were in women in early pregnancy, who received general anaesthesia for gynaecological surgery by inexperienced anaesthetists who failed to manage the airway and ventilation adequately. When trainee anaesthetists are relatively inexperienced their consultants must know the limits of their competence and when close supervision and help may be needed. One death was due to bupivacaine toxicity due to a drug administration error when a bag of dilute local anaesthetic was thought to be intravenous fluid. In a further 31 cases poor perioperative management may have contributed to death. Obesity was again a relevant factor. Other cases could be categorized into poor recognition of women being sick and poor clinical management of haemorrhage, sepsis and of pre-eclampsia. Early warning scores of vital signs may help identify the mother who is seriously ill. Learning points are highlighted in relation to the clinical management of these obstetric complications.

Keywords: anaesthesia, general; anaesthesia, obstetric; anaesthesia, regional; anaesthetic techniques, epidural; complications; early warning scores; toxicity, local anaesthetics


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British Journal of Anaesthesia, 22 Jan 2008 [Full text]
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